Modeling Lymphatic Filariasis Transmission and Eradication

Funded by: National Institutes of Health Country: Papua New Guinea Project Lead: Eck Institute for Global Health

The objective of this project is to develop and validate a dynamic mathematical model firmly rooted in data specific for filariasis transmission by anopheline mosquitoes in Papua New Guinea. This will help define epidemiologically relevant intervention endpoints signifying elimination of transmission and predict the effects of interventions to aid the design, monitoring and evaluation of control strategies against the disease in the country. An additional aim is to compare transmission dynamics and control of lymphatic filariasis across endemic regions by fitting vector-specific transmission models to data from India, a culicine transmission region, and East Africa, a mixed Anopheles-Culex transmission site.